Immune-mediated: Some drugs can trigger an immune response in the body, leading to the production of antibodies that attack and destroy platelets. This immune-mediated destruction of platelets is one of the common mechanisms in drug-induced thrombocytopenia. Examples of drugs associated with immune-mediated DITP include certain antibiotics (such as penicillin and sulfonamides), anti-inflammatory drugs (such as nonsteroidal anti-inflammatory drugs, or NSAIDs), and anticonvulsants.
Non-immune-mediated: Other drugs can cause thrombocytopenia through non-immune mechanisms, such as direct toxicity to the bone marrow where platelets are produced. Chemotherapy drugs, for example, can suppress bone marrow function and lead to a decrease in platelet production.
Drug-induced thrombocytopenia
Drug-induced thrombocytopenia
Reviewed by @DharSaty
on
May 02, 2024
Rating: 5
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh7d8XEnlj8OQPe9c9eFvJbND25OY2aqNi1mlwn16cOp7l8e9lFA59UXDfbyQyNXQEKXMmHlGfAHpL8hD0raHMUnM155MC_18iM45HjD8seaIdwDEn_D-PGU_ypvFdHoGltFUJHtdHcWlmZLgkOum1MvEcRxSIhoPy6g5vDfT2kt9_0W87NiixL2IdsXAkA/s72-w640-c-h437/Thtombocytopenia.jpg)