.png)
Indium
111- tagged white blood cell scan is a type of imaging modality used to help
identify regions of inflammation and thus infections when other imaging studies
are equivocal or contraindicated.
The
test is used for diagnostic purposes in the evaluation of prosthetic joint
infections, osteomyelitis, vascular graft infections, intra-abdominal infections,
abscesses, endocarditis, foot ulcers, infected implanted devices such as
central venous catheters, fevers of unknown origin when there is a high
probability of infection, and Inflammatory bowel disease.
Sensitivity
60 to 100% and specificity 69 to 92%.
White
blood cells are obtained from a blood sample from a patient, are tagged with
the radioisotope indium-111, and then re-injected intravenously into the
patient. These labeled leukocytes localize to a region of inflammation visible
on the whole body or regional nuclear imaging with bone scintigraphy.
Recommended
dose for adults is 0.3 to 0.5 mCi
Prior
IV antibiotics may produce false negative result.
.png)
