Menu

Hemochromatosis

Hemochromatosis is a disorder associated with deposits of excess iron that causes multiple organ dysfunction. Hemochromatosis has been called “bronze diabetes” due to the discoloration of the skin and associated disease of the pancreas. Hereditary hemochromatosis is the most common autosomal recessive disorder in whites. Secondary hemochromatosis occurs because of erythropoiesis disorders and treatment of the diseases with blood transfusions.

A common initial presentation is an asymptomatic patient with mildly elevated liver enzymes who is subsequently found to have elevated serum ferritin and transferrin saturation. Ferritin levels greater than 300 ng per mL for men and 200 ng per mL for women and transferrin saturations greater than 45% are highly suggestive of hereditary hemochromatosis.

Phlebotomy is the mainstay of treatment and can help improve heart function, reduce abnormal skin pigmentation, and lessen the risk of liver complications. Liver transplantation may be considered in select patients. Individuals with hereditary hemochromatosis have an increased risk of hepatocellular carcinoma and colorectal and breast cancers. Genetic testing for the hereditary hemochromatosis genes should be offered after 18 years of age to first-degree relatives of patients with the condition.


Disclaimer

The contents of this website, including text, images, and other information, are not a substitute for medical decisions or professional medical advice. This website is intended for informational and educational purposes only and should not be used for rendering medical guidance. The opinions expressed on this site are solely our own and do not represent the views of any affiliated organization. Images, text, and graphics are sourced from research articles published online and from Google Images/Academic. While we strive to keep the medical information on this website up to date, we cannot guarantee that it reflects the latest research. In case of an emergency, call 911 immediately. For personalized treatment, please consult your doctor. Always seek the advice of a physician or other qualified healthcare professional regarding any questions about a medical condition or treatment. Never disregard or delay seeking professional medical advice because of something you have read on this website. This website does not endorse or recommend any specific tests, doctors, products, procedures, opinions, or other information mentioned herein. By using this website, you acknowledge and agree that it is your responsibility to seek appropriate professional guidance when making medical or health-related decisions. This website and its contributors disclaim any liability arising from the use of the content or images provided herein.

Search This Site

Copy Right @DharSaty

'O' My Dear LORD! Lead us, guide us, inspire us, and remind us to believe in possibilities.